Case Study & Fireside Chat: Modernising Dermatology Trial Design: Reducing Placebo Noise, Updating Endpoints & Strengthening Site Execution

10:00 am - Thursday 21st May 2026

  • Redesigning dermatology endpoints by addressing outdated scales, high placebo response, and the need for validated assessments in understudied diseases where current tools fail to capture meaningful patient change
  • Improving trial integrity through stronger site strategy by prioritising dermatologyspecific expertise, rigorous site preparation, and high-quality CRO oversight to minimise variability, reduce placebo inflation, and ensure reliable clinical evaluation
  • Designing studies that reflect real-world dermatology by incorporating combination therapy considerations, cultural and behavioural adaptations, patient-centred outcomes, and feasible protocols that account for Europe’s fragmented healthcare pathways

Speakers:

Vice President, Clinical Development
Alumis
Vice President, Clinical Development
Nektar Therapeutics